Schematic and details of experiment. Credit: Nature Physics (2025). DOI: 10.1038/s41567-025-02825-9 Living cells are bustling with molecular machines that constantly process energy, matter, and information. Among these machines, proteins stand out, with enzymes being the most notable. These catalytic entities dramatically accelerate essential metabolic reactions by many orders of magnitude, facilitating the very processes that sustain life. While it has lo